Slay the Spire Ascension Guide

How to unlock and beat the ascension mode in Slay the Spire.

Slay The Spire Ascension Guide

Ascension is a special mode that increases the difficulty in Slay the Spire. There are 20 Ascension levels in total, and each of them adds a special modifier that makes the game harder.

As for me, Ascension levels make the game really harder when you reach level 10+. I've played Slay the Spire for over 150 hours but still didn't beat the 20 Ascension level on all 4 characters. However, I've noticed lots of useful tips that might help you on your way to reach Ascension in Slay the Spire.

So, in this Slay the Spire Ascension guide, I will write about everything you need to know about Slay the Spire Ascension mode: what is it, how to unlock it, and tips to beat all the levels.

How does Ascension work in Slay the Spire?

Slay The Spire Ascension Level 19

In Slay the Spire Ascension is a progressive difficulty system that makes the run on each level more challenging. When you play in Ascension mode, you start at Ascension 1 and work your way up through 20 difficult levels.

Each Ascension level adds new modifiers that increase the game's difficulty. These modifiers make enemies stronger, reduce your resources, or add more challenges to each run.

The game modifiers of each Ascension level are added to the previous ones. For example, if you play on Ascension 4, the modifiers of Ascension 1-3 levels will be also added to your game.

Losing a run on any of Slay the Spire Ascension levels will not reset your progress. You will still be able to play your Ascension level. Moreover, you can play any of the Ascension levels you unlocked at any time.

Slay the Spire Ascension List

There are a total of 20 Ascension levels in Slay the Spire. Each level adds a new modifier to the game:

Ascension LevelDescriptionEffect
Ascension 1Elites spawn more oftenThere will be approximately 60% more Elites spawned on a map
Ascension 2Normal enemies are deadlierNormal enemies deal more damage with their attacks
Ascension 3Elites are deadlierElites deal more damage with their attacks
Ascension 4Bosses are deadlierBosses deal more damage with their attacks
Ascension 5Heal less after Boss battlesHeal for 75% of missing health instead of 100%
Ascension 6Start each run damagedLose 10% health at the start of each run
Ascension 7Normal enemies are tougherNormal enemies are harder to take down (more HP, higher Block)
Ascension 8Elites are tougherElites have more HP
Ascension 9Bosses are tougherBosses are harder to take down (more HP, higher Block)
Ascension 10Start each run cursedObtain 1 Ascender's Bane at the start of each run
Ascension 11Start each run with 1 less potion slotYou will have 2 potion slots instead of 3
Ascension 12Upgraded cards appear less oftenUpgraded cards are 25% less likely to appear in Act 2 and 50% in Act 3
Ascension 13Poor bossesBosses drop 25% less gold
Ascension 14Lower max HPCharacters have less HP (-5 for Ironclad, -4 for others)
Ascension 15Unfavorable eventsEvents have less positive outcomes (more HP loss, fewer gold rewards, guaranteed curse)
Ascension 16Shops are more costlyEverything costs 10% more
Ascension 17Normal enemies have more challenging movesets and abilities
Ascension 18Elites have more challenging movesets and abilities
Ascension 19Bosses have more challenging movesets and abilities
Ascension 20Double bossAfter you defeat the first boss in Act 3, you will enter a battle with another one

How to Unlock Ascension

In order to unlock Ascension mode (first level), you should first complete a successful run with the character you're playing. That means you need to defeat the boss from Act 3. 

Each character unlocks Ascension levels separately, so you should complete a successful run with each character to unlock Ascension mode for all the characters in Slay the Spire.

Once you unlock Ascension 1, completing another successful run at that Ascension level will unlock the next level (Ascension 2), and so on.

If you lose a run in Act 4, it will still unlock the next level of Ascension. 

You may also play any of the Ascension levels you have unlocked.

Slay the Spire Ascension Tips

There are lots of tips I've noticed while playing Slay the Spire Ascension. Moreover, I've found a brilliant guide from screwyioux on Reddit about the 20 Ascension level. Below I made some takeaways with tips and strategies from my experience, and the guide of screwyioux.

General Tips Across All Acts

There are some general tips that you may use in any of the Acts in Slay the Spire:
  • Card Removal: As you progress, focus on removing weaker cards and adding draw or manipulation effects to access your deck's strengths more consistently.
  • Adapt Strategy Based on Fights: Tailor your strategy to handle specific threats, such as prioritizing certain enemies or adjusting your playstyle to account for unique boss mechanics.
  • Don't Forget to Use Potions: Do not underestimate the value of potions. They can provide advantages in tough fights.

Ascension Tips for Act 1

  • Focus on Front-Loaded Damage: Aim to maximize your damage output in the first three turns. Single-target damage is good early on, but having one or two AoE options (or potions) can help with later hallway fights.
  • Play Greedy: In Act 1 try to beat as many Elits as possible. You need to take the maximum number of relics and strong cards at this point.
  • Focus on Burst Damage: Build your deck with quick burst damage. Avoid adding too many skills if you might face Nob.

Ascension Tips for Act 2

  • Shift Focus to AoE and Defense: Ensure you have sufficient AoE damage for enemies with higher health pools. Damage mitigation becomes more critical in this act.
  • Prioritize Elite Fights Over Hallway Fights: Elites and question mark events often offer better rewards and are less taxing than the difficult hallway fights.

Ascension Tips for Act 3

  • Focus on Damage Mitigation: Your damage capabilities should be well-established, so shift your focus to cards and relics that provide sustained defense, especially for longer fights.
  • Beware of Reptomancer: Without sufficient front-loaded AoE or quick-kill potential, avoid elite fights due to the risk of encountering Reptomancer.
  • Prepare for All Possible Bosses: Ascension 20 requires preparation for all three potential bosses (Time Eater, Awakened One, Donu and Deca). Tailor your deck to handle each boss's mechanics effectively.

Ascension Tips for Act 4

  • Maximize Your Build's Strengths: The Heart fight and the preceding elite fight will test all aspects of your deck. Ensure you have consistent damage output, scaling, and mitigation.
  • Prepare for Specific Challenges: The Spear and Shield elite fight can be as challenging as an Act 3 boss. Manage debuffs and maximize your deck's capabilities to handle both the elite and the Heart.
  • Keep the Best Potions: Potions are very important in Act 4. Use them strategically to compensate for any weaknesses in your deck.

Ascension Rewards

In Slay the Spire, Ascension mode itself does not provide additional rewards such as new cards, relics, or cosmetic unlocks beyond the base game's unlocks. However, each Ascension level grants a 5% additional score to your rating on the daily challenge leaderboards, up to 100% at Ascension 20 for the following score bonuses:

  1. Floors Climbed
  2. Enemies Killed
  3. Elites Killed
  4. Bosses Slain
  5. Champion
  6. Perfect
  7. Beyond Perfect
  8. Overkill
  9. C-c-c-combo

Conclusion

Ascension is a special mode in Slay the Spire that increases the game's difficulty. There are 20 Ascension levels in total, and each of them adds a new modifier to make the game more difficult.

To unlock the Ascension mode, you need to defeat the boss in Act 3. In the same way, you can unlock the new Ascension levels. Each character has individual progress in Ascension mode.

FAQ

  • How many ascension levels are in Slay the Spire?

    There are 20 Ascension levels in Slay the Spire for each character.

  • What is Ascension in Slay the Spire?

    Ascension is a difficulty mode in Slay the Spire that progressively increases the challenge with each level by adding new modifiers that make enemies stronger, increase costs, and impose restrictions.

  • How to unlock Ascension in Slay the Spire?

    To unlock Ascension for a character, you must first complete the game (defeat the Act 3 boss) with that character. Each victory at an Ascension level unlocks the next level for that character.

  • How to beat Ascension 20 in Slay the Spire?

    Beating Ascension 20 requires careful deck building, focusing on a balance between offense and defense, optimizing pathing to maximize rewards while minimizing damage, and understanding enemy patterns to mitigate damage effectively. Each character has unique strategies that work best, so it's important to adapt your playstyle accordingly.

Interested in some additional guides or help? Check out our Slay the Spire page for more useful tips and guides.

Yaroslav mokliak
Yaroslav Mokliak

CEO | Editor | Content Writer

With over 15 years of playing games and 5 years of writing articles, Yaroslav is a CEO and content creator at HermitGamer. Yaroslav regularly plays video games, creates useful guides, and writes reviews with his opinion on new and old titles. His main goal is to make HermitGamer a platform, where each gamer can find the answers.

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